Posts Tagged Colchicine
Management and Treatment of Gout
Posted by gary in Management and Treatment of Gout on April 30, 2010
The first point of call after you suspect that you have had a gout attack is to see your Doctor for his/hers opinion and treatment.
The information that they would be giving in part would include the information below:
This information is only part of the total to help you in understanding what is the best treatment for you as an individual, a treatment that suits your body and life style
Treatment objectives include managing the symptoms of an acute attacks and preventing further attacks via reducing serum uric acid levels.
Options for treatment include application of cold, nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, and colchicine.
Ice applied for 20 to 30 minutes several times a day decreases pain.
NSAIDS
NSAIDS are the usual first line treatment for gout with no significant difference between agents in effectiveness.
Improvement may be seen within 4 hours. They however are not recommended in those with certain other health problems such as gastrointestinal bleeding, renal failure, or heart failure.
While indomethacin is historically the most commonly used NSAID, due to concerns of side effects and no evidence of greater benefit, an alternative like ibuprofen may be preferred.
For those at risk of gastric irritation from NSAIDs, an additional proton pump inhibitor may be given.
Steroids
Glucocorticoids have been found to be equally effective to NSAIDs and may be used if contraindications exist for NSAIDs.
Intra-articular steroids have also been found to be effective however the risk of concurrent joint infection must be ruled out.
Colchicine
Colchicine is an alternative for those unable to tolerate NSAIDs. Its side effects (primarily gastrointestinal upset) has decreased its usage.
Gastrointestinal upset however depends on the dose and the risk can be decreased by using smaller yet still effective doses.
Colchicine may interact with other commonly prescribed drugs such as atorvastatin and erythromycin among others.
Epidemiology
Gout affects 1% of the Western population at some point in their lifetime and is increasing in prevalence. This increases to 2% in men over the age of 30 and women over the age of 50.
Different populations have different propensities to develop gout. In the United States, gout is twice as prevalent in African American males as it is in European-Americans.
It is high among the peoples of the Pacific Islands, and the Māori of New Zealand, but rare in Australian aborigines despite the latter’s higher mean concentration of serum uric acid
In the United States and Italy, attacks of gout occur more frequently in the spring.
Conclusion
People can react in many ways to all sort of different treatments depending on life styles, diet, and many more propensities to react to different types of gout cures that we as individuals have.The propensities towards any medicene whether it is prescribed or not to react one way or the other is in our make up as individuals make it esential that we evaluate all information and treatments to gives us a way to lead a life style we are looking for and deserve.
Natural Gout Remedies is one way to look at your gout control.
The improvements in todays medicine is such that whatever treatment suits you make sure you have a medical check up by your doctor as required on a regular bases.
